Prof. Christophe Minier
LEMA - Laboratoire d'Ecotoxicologie - Milieux Aquatiques
UPRESS-EA 3222; IFRMP 23, GDR Ifremer IMOPHYS
Université du Havre, BP 540
25, rue Philippe Lebon
76058 Le Havre cedex
tel: (33) 2 32 74 43 03
fax: (33) 2 32 74 43 05
Recognized on the national and international scientific scenes, professor Christophe Minier took an active part in multiple meetings aiming at developing and implementing biomonitoring programmes (e.g. National Oceanic
and Atmospheric Administration; European Environmental Agency, Joint assessment program of the OSPAR convention, French monitoring programmes).
He is head of the unit “Etiology environmental stresses” in the Laboratory of Ecotoxicology at the University of Le Havre and coordinator of research
activities on endocrine disruption for the national consortium “EXECO” comprising 6 French laboratories.
He is also the research leader of the European research programme “Determination of pertinent Indicators for Environmental monitoring: a Strategy for Europe - DIESE”.
Professor Minier’s research interests are in the area of endocrine disruption, environmental genotoxicity and studies on the multixenobiotic resistance (MXR) system. Particular focus lies in the assessment of exposure (bioavailability and interactions with ABC transporters), and effects at
several levels of the biological organization (from molecular components to whole organism) with particular emphasis on reproduction. His finds contributed to the identification and understanding of the effects of endocrine disrupting compounds in freshwater and marine fish at both the individual and population levels.
Professor Christophe Minier carried out two masters, the first in agronomy at the University of Nantes (INRA, 1989) and the second in Cellular and Molecular Biology at the University of Paris V (1991) in France.
He was awarded an IFREMER grant to carry out a PhD thesis in Aquatic Toxicology (1991-1994) and three European grants for post-doctoral studies in Plymouth Marine Laboratory (Natural Environment Research Council) at Plymouth (England), in Consejo Superior de Investigaciones Cientificas (CSIC), in Barcelona (Spain) and at the Laboratory of Ecotoxicology and Ecophysiology, at ISOMer in Nantes (France).
In 1996, he started a tenure track position of Lecturer at the University of Le Havre where he contributed to the creation and development of the Laboratory of Ecotoxicology - Aquatic environments (LEMA). In 2004 he was awarded an HDR for his research activity and he is now a Professor at the University of Le Havre.
Management and expertise
Professor Minier is an active member of the French society of Ecotoxicology (SEFA) and guest editor or the International Journal of Marine Environmental Research. He is a regular reviewer of numerous international research projects and one of the experts of the French agency for assessment of
research Quality (AERES).
Recent publications (2008-2009)
- Ketata I. Denier X., Chaffai A. & Minier C. 2008. Endocrine-related reproductive effects in molluscs.
Comp. Biochem. Physiol. 147: 261-270.
- Denier X., Couteau J., Baudrimont M., Hill E. M., Rotchell J. & Minier C. 2008. In vitro study of the
effects of cadmium on the activation of the estrogen response element using the YES screen Mar. Environ. Res. 66 : 108-110.
- Couteau J., Flaman J-M., Minier C. & Cachot J. 2008. Detection of environmental mutagens using the Facim assay. Mar. Environ. Res. 66 : 62-63.
Guérit I., Bocquené G., James A., Thybaud E., Minier C. 2008. Environmental risk assessment: a critical approach of the European TGD in an in situ application. Ecotox. Environ. Safe. 71:291-300.
- Mouneyrac C., Linot S., Amiard J-C., Amiard-Triquet C., Métais I., Durou C., Minier C., Pellerin J. 2008. Biological indices, energy reserves, steroid hormones and sexual maturity in the infaunal bivalve Scrobicularia plana from three sites differing by their level of contamination. Gen.
Comp. Endocrinol. 157: 133-141.
- Minier C., Forget-Leray J., Bjørnstad A., Camus L. 2008. Multixenobiotic resistance, acetyl-choline esterase activity and total oxyradical scavenging capacity of the Arctic spider crab, Hyas
araneus, following exposure to Bisphenol A, Tetra Bromo Diphenyl Ether and Diallyl phtalate. Mar. Pollut. Bull. 56: 1410-1415.
- Amiard J.-C., Bodineau L., Bragigand V., Minier C & Budzinski H. 2008. Quantification of contaminants. In Amiard-Triquet C. and Rainbow P.S., Environmental assessment of
estuarine ecosystems. Taylor and Francis. Boca Raton. 31-58.
- Minier, C., Amara R. 2008. From pollution to altered fish physiological performance; the case of flatfish in the Seine estuary. In Amiard-Triquet Environmental assessment of estuarine ecosystems. Taylor and Francis. Boca Raton. 227-240.
- Amara R., Selleslagh J., Billon G., Minier C. 2009. Growth and condition of 0-group European flounder, Platichthys flesus as indicator of estuarine habitat quality. Hydrobiologia. 627: 87-98.
- Denier X., Hill E.M., Rotchell J., Minier C. 2009. Estrogenic activity of cadmium, copper and zinc in the yeast-estrogen screen. Toxicol. In Vitro. 569-573.
- Geraudie P., Gerbron M., Hill E., Minier C. 2009. Roach (Rutilus rutilus) reproduction: a study of biochemical and histological parameters in a low contaminated site. Fish. Physiol. Biochem. In press. DOI: 10.1007/s10695-009-9351-5.
- Geraudie P., Lecomte C., Gerbron M., Hinfray N., Brion F., Minier C. 2009. Endocrine effects of the tapeworm Ligula intestinalis in its teleost host, the roach (Rutilus rutilus). Parasitology. 136:1-8.
- Geraudie P., Gerbron M., Minier C. Seasonal variations and alteration of sex steroid levels during the reproductive cycle of the roach (Rutilus rutilus). Mar. Environ. Res. Submitted.